Precorrin-6A reductase

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precorrin-6A reductase
Identifiers
EC number 1.3.1.54
CAS number 137672-84-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a precorrin-6A reductase (EC 1.3.1.54) is an enzyme that catalyzes the chemical reaction

precorrin-6B + NADP+ \rightleftharpoons precorrin-6A + NADPH + H+

Thus, the two substrates of this enzyme are precorrin 6B and NADP+, whereas its 3 products are precorrin 6A, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is precorrin-6B:NADP+ oxidoreductase. Other names in common use include precorrin-6X reductase, and precorrin-6Y:NADP+ oxidoreductase. This enzyme participates in porphyrin and chlorophyll metabolism.

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