Precorrin-6A synthase (deacetylating)

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precorrin-6A synthase (deacetylating)
Identifiers
EC number 2.1.1.152
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a precorrin-6A synthase (deacetylating) (EC 2.1.1.152) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + precorrin-5 + H2O \rightleftharpoons S-adenosyl-L-homocysteine + precorrin-6A + acetate

The 3 substrates of this enzyme are S-adenosyl methionine, precorrin 5, and H2O, whereas its 3 products are S-adenosylhomocysteine, precorrin 6A, and acetate.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating). Other names in common use include precorrin-6X synthase (deacetylating), and CobF. This enzyme participates in porphyrin and chlorophyll metabolism.

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