Premature rupture of membranes

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Premature rupture of membranes
Classification and external resources
ICD-10	O42.
ICD-9	658.1
DiseasesDB	10600
eMedicine	med/3246
MeSH	D005322

Premature rupture of membranes (PROM) is a condition which occurs in pregnancy when the amniotic sac ruptures more than an hour before the onset of labor. PROM is prolonged when it occurs more than 18 hours before labor. PROM is preterm (PPROM) when it occurs before 37 weeks gestation.^[1] Risk factors for PROM can be a bacterial infection, smoking, or anatomic defect in the structure of the amniotic sac, uterus, or cervix. In some cases, the rupture can spontaneously heal, but in most cases of PPROM, labor begins within 48 hours. When this occurs, it is necessary that the mother receive treatment to avoid possible infection in the newborn.^[2]

[edit] Management

If chorioamnionitis is present at the time of PPROM, antibiotic therapy is usually given to avoid sepsis, and delivery is indicated. If chorioamnionitis is not present, prompt antibiotic therapy can significantly delay delivery, giving the fetus crucial additional time to mature.^[3]

[edit] References

[edit] See Also

Placental_alpha_microglobulin-1_(PAMG-1) 

v • d • e Pathology of pregnancy, childbirth and the puerperium (O, 630-676) Complications of pregnancy Pregnancy with abortive outcome Ectopic pregnancy · Hydatidiform mole · Miscarriage Oedema, proteinuria and hypertensive disorders Gestational hypertension (Pre-eclampsia, Eclampsia, HELLP syndrome) · Gestational diabetes Other, predominantly related to pregnancy digestive system: Hyperemesis gravidarum · Intrahepatic cholestasis of pregnancy · Acute fatty liver of pregnancy integumentary system: Dermatoses of pregnancy (list) nervous system: Chorea gravidarum Maternal care related to the fetus and amniotic cavity amniotic fluid (Polyhydramnios, Oligohydramnios) · chorion/amnion (Chorioamnionitis, Chorionic hematoma, Premature rupture of membranes, Amniotic band syndrome, Monoamniotic twins) · placenta (Placenta praevia, Placental abruption, Monochorionic twins, Twin-to-twin transfusion syndrome) · Braxton Hicks contractions · Antepartum haemorrhage Obstetric labor complications Preterm birth · Postmature birth · Cephalopelvic disproportion · Dystocia (Shoulder dystocia) · Fetal distress · Vasa praevia · Uterine rupture · hemorrhage · placenta (Placenta accreta) · Umbilical cord prolapse · Amniotic fluid embolism Puerperal disorders Puerperal fever · Peripartum cardiomyopathy · Postpartum thyroiditis · Galactorrhea · Postpartum depression · Diastasis symphysis pubis Other Maternal death obstetric navs: conditions, eponymous signs, proc

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