Prime Hook National Wildlife Refuge is an inviolate sanctuary expressly for migratory birds, located east of Milton, Delaware. It was established in 1963 on 10,000 acres (40 km2) along the western shore of Delaware Bay. The refuge contains a variety of habitats, including freshwater and salt marshes, woodlands, grasslands, ponds, and forested areas, supporting 267 species of birds and a variety of reptiles, amphibians and mammals.
The refuge is open to the public for wildlife-oriented recreation. Facilities include walking trails, a canoe trail, a bird blind and other wildlife observation areas, and a visitors center.