Procaterol

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Procaterol
(±)-Procaterol Enantiomers Structural Formula.png
Systematic (IUPAC) name
(±)-(1R,2S)-rel-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-quinolin-2(1H)-one
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
Legal status
?
Routes Oral, inhalation
Identifiers
CAS number 59828-07-8 YesY
ATC code R03AC16 R03CC08
PubChem CID 4916
ChemSpider 599984 N
UNII X7I3EMM5K0 YesY
KEGG D08424 YesY
Chemical data
Formula C16H22N2O3 
Mol. mass 290.357 g/mol
 N (what is this?)  (verify)

Procaterol, applied as procaterol hydrochloride (USAN), is an intermediate-acting β2-adrenergic receptor agonist used for the treatment of asthma. It has never been filed for FDA evaluation in the United States, where it is not marketed. The drug is readily oxidised in the presence of moisture and air, making it unsuitable for therapeutic use by inhalation.[1] Pharmaceutical company Parke-Davis/Warner-Lambert researched a stabilizer to prevent oxidation, but an effective one was never developed.[1]

References[edit]

  1. ^ a b US 4616022, Ghebre-sellassie, Issac & Russell U. Nesbitt Jr., "Procaterol stabilization", published 1984, issued 1986