Profadol

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Not to be confused with Propofol.
Profadol
Profadol skeletal.svg
Systematic (IUPAC) name
3-(1-methyl-3-propyl-pyrrolidin-3-yl)phenol
Clinical data
Legal status
  • Schedule II (Analogue of Tapentadol) (US)
Identifiers
CAS number 428-37-5
ATC code None
PubChem CID 9882
ChemSpider 9498
UNII 41GDG43FTT YesY
ChEMBL CHEMBL161204
Chemical data
Formula C14H21NO 
Mol. mass 219.32 g/mol

Profadol (CI-572) is an opioid analgesic which was developed in the 1960s by Parke-Davis.[1] It acts as a mixed agonist-antagonist of the μ-opioid receptor. The analgetic potency is about the same as of pethidine (meperidine), the antagonistic effect is 1/50 of Nalorphine.[2]

See also[edit]

References[edit]

  1. ^ DE Patent 1303096
  2. ^ Eberhard Schröder, Clemens Rufer, Ralph Schmiechen, Arzneimittelchemie I, Georg Thieme Verlag 1976 ISBN 3-13-520601-7