Progress M1-10 was launched by a Soyuz-U carrier rocket from Site 1/5 at the Baikonur Cosmodrome. Launch occurred at 10:34 GMT on 8 June 2003. The spacecraft docked with the Pirs module at 11:14:53 GMT on 11 June. It remained docked for three months before undocking at 19:41:44 GMT on 4 September to make way for Soyuz TMA-3. Following undocking, it remained in orbit for a month, conducting an earth observation mission. It was deorbited at 11:26 GMT on 3 October, burning up in the atmosphere over the Pacific Ocean, with any remaining debris landing in the ocean at around 12:38:49 GMT.
Progress M1-10 carried supplies to the International Space Station, including food, water and oxygen for the crew and equipment for conducting scientific research.
Payloads are separated by bullets ( · ), launches by pipes ( | ). Manned flights are indicated in bold text. Uncatalogued launch failures are listed in italics. Payloads deployed from other spacecraft are denoted in brackets.