Prolactin-releasing peptide receptor

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Prolactin releasing hormone receptor
Symbols PRLHR ; GPR10; GR3; PrRPR
External IDs OMIM600895 MGI2135956 HomoloGene3134 IUPHAR: 337 ChEMBL: 1681611 GeneCards: PRLHR Gene
Species Human Mouse
Entrez 2834 226278
Ensembl ENSG00000119973 ENSMUSG00000045052
UniProt P49683 Q6VMN6
RefSeq (mRNA) NM_004248 NM_201615
RefSeq (protein) NP_004239 NP_963909
Location (UCSC) Chr 10:
120.35 – 120.36 Mb
Chr 19:
60.47 – 60.47 Mb
PubMed search [1] [2]

The prolactin-releasing peptide receptor (PrRPR) also known as G-protein coupled receptor 10 (GPR10) is a protein that in humans is encoded by the PRLHR gene.

PrRPR is a G-protein coupled receptor[1] that binds the prolactin-releasing peptide (PRLH).[2]


PrRPR is a 7-transmembrane domain receptor for prolactin-releasing peptide that is highly expressed in the anterior pituitary.[3]


  1. ^ Marchese A, Heiber M, Nguyen T, Heng HH, Saldivia VR, Cheng R, Murphy PM, Tsui LC, Shi X, Gregor P (1995). "Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors". Genomics 29 (2): 335–44. doi:10.1006/geno.1995.9996. PMID 8666380. 
  2. ^ Hinuma S, Habata Y, Fujii R, Kawamata Y, Hosoya M, Fukusumi S, Kitada C, Masuo Y, Asano T, Matsumoto H, Sekiguchi M, Kurokawa T, Nishimura O, Onda H, Fujino M (1998). "A prolactin-releasing peptide in the brain". Nature 393 (6682): 272–6. doi:10.1038/30515. PMID 9607765. 
  3. ^ "Entrez Gene: PRLHR prolactin releasing hormone receptor". 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.