Propiconazole

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Propiconazole[1]
Propiconazole.png
Identifiers
CAS number 60207-90-1 YesY
PubChem 43234
ChemSpider 39402 YesY
UNII 142KW8TBSR YesY
KEGG C11121 YesY
ChEBI CHEBI:8489 YesY
ChEMBL CHEMBL560579 YesY
Jmol-3D images Image 1
Properties
Molecular formula C15H17Cl2N3O2
Molar mass 342.22038
Boiling point 180 °C at 0.1 mmHg [1]
Solubility in water 100 ppm at 20 °C
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY (verify) (what is: YesY/N?)
Infobox references

Propiconazole is a triazole fungicide, also known as a DMI, or demethylation inhibiting fungicide due to its binding with and inhibiting the 14-alpha demethylase enzyme from demethylating a precursor to ergosterol. Without this demethylation step, the ergosterols are not incorporated into the growing fungal cell membranes, and cellular growth is stopped. Propiconazole is used agriculturally on turfgrasses grown for seed and aesthetic or athletic value, mushrooms, corn, wild rice, peanuts, almonds, sorghum, oats, pecans, apricots, peaches, nectarines, plums and prunes.[2] It is also used in combination with permethrin in formulations of wood preserver.[3] Propiconazole is a mixture[4] of four stereoisomers and was first developed in 1979 by Janssen Pharmaceutica.[5]

References[edit]

  1. ^ Merck Index, 11th Edition, 7830.
  2. ^ EXTOXNET
  3. ^ See entry for Complete Wood Preservative
  4. ^ L. Toribio, M. J. del Nozal, J. L. Bernal, J. J. Jeménez und C. Alonso, J. Chromatography A 2004, 1046, 249-253.
  5. ^ W. T. Thomson. 1997. Agricultural Chemicals. Book IV: Fungicides. 12th edition. Thomson Publications, Fresno, CA

External links[edit]