In pharmacology, a psycholeptic is a medication which produces a calming effect upon the patient. Such medications include barbiturates, benzodiazepines, nonbenzodiazepines, phenothiazines, opiates/opioids, carbamates, ethanol, 2-methyl-2-butanol, cannabinoids (in some classifications), some antidepressants, neuroleptics, and some anticonvulsants. Many herbal medicines may also be classified as psycholeptics (ex. kava, valerian).
The psycholeptics are classified under N05 in the Anatomical Therapeutic Chemical Classification System.