The team was founded in 1927 by a group of students led by Noriega brothers, but it wasn't until 1931 when Pumas was officially the varsity team of National Autonomous University of Mexico. In addition, American oil magnate Harry Ford Sinclair sponsored the team with generous donations until 1935. In the early years, Pumas had a long string of consecutive championships from 1933 to 1945 (including an appearance in the 1945 Sun Bowl; this was followed by the so-called "Golden Age" of 1946 to 1957. Between the years 1958 and 1969 the team consolidated its position within ONEFA, Mexico's league of American football. For the period 1970-1980 the university authorities decided to disband the team and create three teams (Cóndores / Condors; Aguilas Reales / Royal Eagles; and Guerreros Aztecas / Aztec Warriors), from 1981 to 1990 only the Cóndores could reclaim the tradition of the Pumas and win championships. In 1998, the University government decided to reduced to one team per campus and created Pumas CU and Acatlan. Unfortunately, conditions within the league and the existence of other powerful newcomer squads undermined the strength and dominance of the team. Its first position tradition vanished rapidly during the seasons of 1998 to 2007. Pumas Dorados has been represented since 1969 by a selection of the best players of all UNAM teams until 2002, they didn't play any regular season game, though. Pumas Dorados used to play a Classic game against Burros Blancos at the end of season until 2002 when it was suspended.
In 2008 was created another league for the major category in Mexico (Liga Mayor) and the National Championship is shared in 2 leagues since then.
+ This is not the same team as previous Pumas Dorados teams. Championships in 2008 and 2010 were won by the Main Campus (CU). There is another Pumas team located in Acatlan Campus. Pumas Dorados currently represents a selection of the best players of both Pumas teams and the last selection was made in 2002 and played against a selection of the best players of the IPN.