Puyuhuapi (from the Mapudungun puye, small fish and huapi, island), also Cai Channel (NGA UFI=-897934) is a sea channel separating Magdalena Island from the mainland of Aysén del General Carlos Ibáñez del Campo Region in Chile. The channel runs through a branch of the Liquiñe-Ofqui Fault. The main settlement in the channel is Puerto Cisnes.
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