Two medical condition associated with the pylorus is pyloric stenosis. One method of relieving this partial or complete obstruction is the surgical placement of a pyloric stent. This stent is synthetic tube which maintains patency between the stomach and proximal duodenum.
In such conditions as stomach cancer, tumours may partly block the pyloric canal. A special tube can be implanted surgically to connect the stomach to the duodenum so as to facilitate the passage of food from one to the other. This tube is called a gastroduodenostomy.