Quinethazone

Quinethazone

Systematic (IUPAC) name
7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline- 6-sulfonamide
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral
Identifiers
CAS number	73-49-4 Y
ATC code	C03BA02
PubChem	CID 6307
DrugBank	DB01325
ChemSpider	6068 Y
UNII	455E0S048W Y
KEGG	D00461 Y
ChEMBL	CHEMBL1532 Y
Chemical data
Formula	C10H12ClN3O3S
Mol. mass	289.739 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C10H12ClN3O3S/c1-2-9-13-7-4-6(11)8(18(12,16)17)3-5(7)10(15)14-9/h3-4,9,13H,2H2,1H3,(H,14,15)(H2,12,16,17) Y Key:AGMMTXLNIQSRCG-UHFFFAOYSA-N Y
Y (what is this?)  (verify)

Quinethazone (INN, brand name Hydromox) is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.

Synthesis

References

Cohen, Elliott; Klarberg, Betty; Vaughan, James R. (1960). Journal of the American Chemical Society 82 (11): 2731. doi:10.1021/ja01496a020.