RAB3D

RAB3D, member RAS oncogene family
PDB rendering based on 2gf9.
Available structures PDB 2gf9
Identifiers
Symbols	RAB3D; D2-2; GOV; RAB16; RAD3D
External IDs	OMIM: 604350 MGI: 97844 HomoloGene: 20902 GeneCards: RAB3D Gene
Gene Ontology Molecular function • nucleotide binding • GTPase activity • GTP binding • GTPase binding Cellular component • mitochondrion • plasma membrane • transport vesicle • zymogen granule Biological process • GTP catabolic process • small GTPase mediated signal transduction • protein transport • regulation of exocytosis • peptidyl-cysteine methylation Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9545	19340
Ensembl	ENSG00000105514	ENSMUSG00000019066
UniProt	O95716	Q543Q4
RefSeq (mRNA)	NM_004283	NM_031874.4
RefSeq (protein)	NP_004274	NP_114080.2
Location (UCSC)	Chr 19: 11.43 – 11.45 Mb	Chr 9: 21.71 – 21.72 Mb
PubMed search	[1]	[2]

Ras-related protein Rab-3D is a protein that in humans is encoded by the RAB3D gene.

Further reading

• Brondyk WH, McKiernan CJ, Fortner KA et al (1995). "Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A". Mol. Cell. Biol. 15 (3): 1137–43. PMC 230335. PMID 7532276. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=230335. 
• Sehgal A, Keener C, Boynton AL et al (1997). "Isolation and characterization of a novel gene from human glioblastoma multiforme tumor tissue". Int. J. Cancer 71 (4): 565–72. doi:10.1002/(SICI)1097-0215(19970516)71:4<565::AID-IJC10>3.0.CO;2-B. PMID 9178809. 
• Raffaniello RD, Raufman JP (1999). "Cytosolic RAB3D is associated with RAB escort protein (REP), not RAB-GDP dissociation inhibitor (GDI), in dispersed chief cells from guinea pig stomach". J. Cell. Biochem. 72 (4): 540–8. doi:10.1002/(SICI)1097-4644(19990315)72:4<540::AID-JCB9>3.0.CO;2-D. PMID 10022613. 
• Cartel NJ, Wang J, Post M (2002). "Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt". Biochem. J. 363 (Pt 1): 19–28. doi:10.1042/0264-6021:3630019. PMC 1222446. PMID 11903042. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1222446. 
• Riedel D, Antonin W, Fernandez-Chacon R et al (2002). "Rab3D Is Not Required for Exocrine Exocytosis but for Maintenance of Normally Sized Secretory Granules". Mol. Cell. Biol. 22 (18): 6487–97. doi:10.1128/MCB.22.18.6487-6497.2002. PMC 135623. PMID 12192047. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=135623. 
• Strausberg RL, Feingold EA, Grouse LH et al (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829. 
• Nguyen D, Jones A, Ojakian GK et al (2003). "Rab3D redistribution and function in rat parotid acini". J. Cell. Physiol. 197 (3): 400–8. doi:10.1002/jcp.10373. PMID 14566969. 
• Matsumoto M, Miki T, Shibasaki T et al (2004). "Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells". Proc. Natl. Acad. Sci. U.S.A. 101 (22): 8313–8. doi:10.1073/pnas.0306709101. PMC 420391. PMID 15159548. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=420391. 
• Knop M, Aareskjold E, Bode G, Gerke V (2005). "Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial cells". EMBO J. 23 (15): 2982–92. doi:10.1038/sj.emboj.7600319. PMC 514934. PMID 15257287. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=514934. 
• Gerhard DS, Wagner L, Feingold EA et al (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Rual JF, Venkatesan K, Hao T et al (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.