RABEPK

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Rab9 effector protein with kelch motifs
Identifiers
Symbols RABEPK ; RAB9P40; bA65N13.1; p40
External IDs OMIM605962 MGI2139530 HomoloGene48772 GeneCards: RABEPK Gene
RNA expression pattern
PBB GE RABEPK 203150 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10244 227746
Ensembl ENSG00000136933 ENSMUSG00000070953
UniProt Q7Z6M1 Q8VCH5
RefSeq (mRNA) NM_001174152 NM_145522
RefSeq (protein) NP_001167623 NP_663497
Location (UCSC) Chr 9:
127.96 – 128 Mb
Chr 2:
34.78 – 34.8 Mb
PubMed search [1] [2]

Rab9 effector protein with Kelch motifs also known as p40 is a protein that in humans is encoded by the RABEPK gene.[1][2]

Membrane-associated p40, in together with RAB9A, facilitates the transport of the mannose 6-phosphate receptor (MPR) from endosomes to the trans-Golgi network.[1]

Interactions[edit]

RABEPK has been shown to interact with RAB9A[1] and FYVE finger-containing phosphoinositide kinase.[3]

References[edit]

  1. ^ a b c Diaz E, Schimmoller F, Pfeffer SR (Aug 1997). "A novel Rab9 effector required for endosome-to-TGN transport". J Cell Biol 138 (2): 283–90. doi:10.1083/jcb.138.2.283. PMC 2138197. PMID 9230071. 
  2. ^ "Entrez Gene: RABEPK Rab9 effector protein with kelch motifs". 
  3. ^ Ikonomov, Ognian C; Sbrissa Diego; Mlak Krzysztof; Deeb Robert; Fligger Jason; Soans Aleric; Finley Russell L; Shisheva Assia (Dec 2003). "Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40". J. Biol. Chem. (United States) 278 (51): 50863–71. doi:10.1074/jbc.M307260200. ISSN 0021-9258. PMID 14530284. 

Further reading[edit]

External links[edit]