RAPGEF6

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Rap guanine nucleotide exchange factor (GEF) 6
Protein RAPGEF6 PDB 2d93.png
PDB rendering based on 2d93.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols RAPGEF6 ; KIA001LB; PDZ-GEF2; PDZGEF2; RA-GEF-2; RAGEF2
External IDs OMIM610499 MGI2384761 HomoloGene22968 GeneCards: RAPGEF6 Gene
Orthologs
Species Human Mouse
Entrez 51735 192786
Ensembl ENSG00000158987 ENSMUSG00000037533
UniProt Q8TEU7 Q5DTR1
RefSeq (mRNA) NM_001164386 NM_001252494
RefSeq (protein) NP_001157858 NP_001239423
Location (UCSC) Chr 5:
130.76 – 130.97 Mb
Chr 11:
54.52 – 54.7 Mb
PubMed search [1] [2]

Rap guanine nucleotide exchange factor 6 is a protein that in humans is encoded by the RAPGEF6 gene.[1][2][3]


References[edit]

  1. ^ Gao X, Satoh T, Liao Y, Song C, Hu CD, Kariya Ki K, Kataoka T (Nov 2001). "Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras". J Biol Chem 276 (45): 42219–42225. doi:10.1074/jbc.M105760200. PMID 11524421. 
  2. ^ Kozlov G, Banville D, Gehring K, Ekiel I (Jul 2002). "Solution structure of the PDZ2 domain from cytosolic human phosphatase hPTP1E complexed with a peptide reveals contribution of the beta2-beta3 loop to PDZ domain-ligand interactions". J Mol Biol 320 (4): 813–820. doi:10.1016/S0022-2836(02)00544-2. PMID 12095257. 
  3. ^ "Entrez Gene: RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6". 

Further reading[edit]