RNA-binding protein 39 is a protein that in humans is encoded by the RBM39gene.
The protein encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it colocalizes with core spliceosomal proteins. Studies of a mouse protein with high sequence similarity to this protein suggest that this protein may act as a transcriptional coactivator for JUN/AP-1 and estrogen receptors. Multiple transcript variants encoding different isoforms have been observed for this gene.
^ abcJung, Dong-Ju; Na Soon-Young; Na Doe Sun; Lee Jae Woon (Jan 2002). "Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors". J. Biol. Chem. (United States) 277 (2): 1229–34. doi:10.1074/jbc.M110417200. ISSN0021-9258. PMID11704680.
Jung DJ, Na SY, Na DS, Lee JW (2002). "Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors". J. Biol. Chem.277 (2): 1229–34. doi:10.1074/jbc.M110417200. PMID11704680.
Deloukas P, Matthews LH, Ashurst J et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature414 (6866): 865–71. doi:10.1038/414865a. PMID11780052.
Lehner B, Semple JI, Brown SE et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID14667819.
Dowhan DH, Hong EP, Auboeuf D et al. (2005). "Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta". Mol. Cell17 (3): 429–39. doi:10.1016/j.molcel.2004.12.025. PMID15694343.
Sun NN, Fastje CD, Wong SS et al. (2005). "Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line". Toxicology and industrial health19 (7–10): 157–63. doi:10.1191/0748233703th185oa. PMID15747776.