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Ras converting CAAX endopeptidase 1
Symbols RCE1 ; FACE2; RCE1A; RCE1B
External IDs OMIM605385 MGI1336895 HomoloGene3769 ChEMBL: 3411 GeneCards: RCE1 Gene
EC number 3.4.22.-
RNA expression pattern
PBB GE RCE1 205333 s at tn.png
More reference expression data
Species Human Mouse
Entrez 9986 19671
Ensembl ENSG00000173653 ENSMUSG00000024889
UniProt Q9Y256 P57791
RefSeq (mRNA) NM_001032279 NM_023131
RefSeq (protein) NP_001027450 NP_075620
Location (UCSC) Chr 11:
66.61 – 66.61 Mb
Chr 19:
4.62 – 4.63 Mb
PubMed search [1] [2]

CAAX prenyl protease 2 is an enzyme that in humans is encoded by the RCE1 gene.[1][2][3]

This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins.[3]


  1. ^ Otto JC, Kim E, Young SG, Casey PJ (Apr 1999). "Cloning and characterization of a mammalian prenyl protein-specific protease". J Biol Chem 274 (13): 8379–82. doi:10.1074/jbc.274.13.8379. PMID 10085068. 
  2. ^ Freije JM, Blay P, Pendas AM, Cadinanos J, Crespo P, Lopez-Otin C (Jul 1999). "Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins". Genomics 58 (3): 270–80. doi:10.1006/geno.1999.5834. PMID 10373325. 
  3. ^ a b "Entrez Gene: RCE1 RCE1 homolog, prenyl protein peptidase (S. cerevisiae)". 

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