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RNA guanylyltransferase and 5'-phosphatase
Protein RNGTT PDB 1i9s.png
PDB rendering based on 1i9s.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols RNGTT ; CAP1A; HCE; HCE1; hCAP
External IDs OMIM603512 MGI1329041 HomoloGene37851 GeneCards: RNGTT Gene
EC number,
RNA expression pattern
PBB GE RNGTT 204207 s at tn.png
PBB GE RNGTT 204208 at tn.png
PBB GE RNGTT 211849 s at tn.png
More reference expression data
Species Human Mouse
Entrez 8732 24018
Ensembl ENSG00000111880 ENSMUSG00000028274
UniProt O60942 O55236
RefSeq (mRNA) NM_001286426 NM_011884
RefSeq (protein) NP_001273355 NP_036014
Location (UCSC) Chr 6:
89.32 – 89.67 Mb
Chr 4:
33.31 – 33.5 Mb
PubMed search [1] [2]

mRNA-capping enzyme is a protein that in humans is encoded by the RNGTT gene.[1][2][3]


  1. ^ Pillutla RC, Shimamoto A, Furuichi Y, Shatkin AJ (Jan 1999). "Human mRNA capping enzyme (RNGTT) and cap methyltransferase (RNMT) map to 6q16 and 18p11.22-p11.23, respectively". Genomics 54 (2): 351–3. doi:10.1006/geno.1998.5604. PMID 9828141. 
  2. ^ Yamada-Okabe T, Doi R, Shimmi O, Arisawa M, Yamada-Okabe H (May 1998). "Isolation and characterization of a human cDNA for mRNA 5'-capping enzyme". Nucleic Acids Res 26 (7): 1700–6. doi:10.1093/nar/26.7.1700. PMC 147440. PMID 9512541. 
  3. ^ "Entrez Gene: RNGTT RNA guanylyltransferase and 5'-phosphatase". 

Further reading[edit]