RPS15

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Ribosomal protein S15
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols RPS15 ; RIG; S15
External IDs OMIM180535 MGI3647234 HomoloGene110643 GeneCards: RPS15 Gene
Orthologs
Species Human Mouse
Entrez 6209 20054
Ensembl ENSG00000115268 ENSMUSG00000063457
UniProt P62841 P62843
RefSeq (mRNA) NM_001018 NM_009091
RefSeq (protein) NP_001009 NP_033117
Location (UCSC) Chr 19:
1.44 – 1.44 Mb
Chr 10:
80.29 – 80.29 Mb
PubMed search [1] [2]

40S ribosomal protein S15 is a protein that in humans is encoded by the RPS15 gene.[1][2]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19P family of ribosomal proteins. It is located in the cytoplasm. This gene has been found to be activated in various tumors, such as insulinomas, esophageal cancers, and colon cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[2]

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