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RU-28306 structure.png
Clinical data
Legal status
CAS number 73625-11-3
ATC code ?
PubChem CID 194528
ChemSpider 168785
Chemical data
Formula C13H16N2 
Mol. mass 200.279 g/mol

RU-28306 is a tricyclic tryptamine derivative which acts as a serotonin receptor agonist, with selectivity for 5-HT1 and 5-HT2 subtypes. It can be regarded either as a conformationally constrained derivative of DMT, or a structurally simplified analogue of LSD, but the binding affinity of racemic RU-28306 is closer to that of DMT, though with relatively higher affinity for 5-HT2 subtypes and lower for 5-HT1.[1]

See also[edit]


  1. ^ Taylor EW, Nikam S, Weck B, Martin A, Nelson D. Relative selectivity of some conformationally constrained tryptamine analogs at 5-HT1, 5-HT1A and 5-HT2 recognition sites. Life Sciences. 1987 Oct 19;41(16):1961-9. PMID 3657392