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RUN and FYVE domain containing 1
Protein RUFY1 PDB 2YQM.png
Rendering based on PDB 2YQM.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols RUFY1 ; RABIP4; ZFYVE12
External IDs OMIM610327 MGI2429762 HomoloGene23522 GeneCards: RUFY1 Gene
RNA expression pattern
PBB GE RUFY1 218243 at tn.png
More reference expression data
Species Human Mouse
Entrez 80230 216724
Ensembl ENSG00000176783 ENSMUSG00000020375
UniProt Q96T51 Q8BIJ7
RefSeq (mRNA) NM_001040451 NM_172557
RefSeq (protein) NP_001035541 NP_766145
Location (UCSC) Chr 5:
178.98 – 179.04 Mb
Chr 11:
50.39 – 50.43 Mb
PubMed search [1] [2]

RUN and FYVE domain-containing protein 1 is a protein that in humans is encoded by the RUFY1 gene.[1][2] It is named after the RUN and FYVE domains it contains.


RUFY1 has been shown to interact with BMX.[1]


  1. ^ a b Yang J, Kim O, Wu J, Qiu Y (Aug 2002). "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking". J. Biol. Chem. 277 (33): 30219–26. doi:10.1074/jbc.M111933200. PMID 11877430. 
  2. ^ "Entrez Gene: RUFY1 RUN and FYVE domain containing 1". 

Further reading[edit]