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Ryanodine receptor 3
Available structures
PDB Ortholog search: PDBe, RCSB
Symbol RYR3
External IDs OMIM180903 MGI99684 HomoloGene68151 IUPHAR: 749 ChEMBL: 2062 GeneCards: RYR3 Gene
Species Human Mouse
Entrez 6263 20192
Ensembl ENSG00000198838 ENSMUSG00000057378
UniProt Q15413 A2AGL3
RefSeq (mRNA) NM_001036 NM_177652
RefSeq (protein) NP_001027 NP_808320
Location (UCSC) Chr 15:
33.6 – 34.16 Mb
Chr 2:
112.63 – 113.22 Mb
PubMed search [1] [2]

Ryanodine receptor 3 is a protein that in humans is encoded by the RYR3 gene.[1][1] The protein encoded by this gene is both a calcium channel and a receptor for the plant alkaloid ryanodine. RYR3 and RYR1 control the resting calcium ion concentration in skeletal muscle.[2]

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  1. ^ a b Sorrentino V, Giannini G, Malzac P, Mattei MG (Feb 1994). "Localization of a novel ryanodine receptor gene (RYR3) to human chromosome 15q14-q15 by in situ hybridization". Genomics 18 (1): 163–5. doi:10.1006/geno.1993.1446. PMID 8276408. 
  2. ^ Perez CF, López JR, Allen PD (March 2005). "Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle". Am. J. Physiol., Cell Physiol. 288 (3): C640–9. doi:10.1152/ajpcell.00407.2004. PMID 15548569. 

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