Raghunatha Shiromani (Bengali: রঘুনাথ শিরোমণি, IAST: Raghunātha Śiromaṇi) (c. 1477–1547) was an Indianphilosopher and logician. He was born at Nabadwip in present day Nadia district of West Bengal state. He was the grandson of Śulapāṇi (c. 14th century CE), a noted writer on Smṛti from his mother's side. He was a pupil of Vāsudeva Sārvabhauma. He brought the new school of Nyaya, Navya Nyāya, representing the final development of Indian formal logic, to its zenith of analytic power.
Raghunatha's analysis of relations revealed the true nature of number, inseparable from the abstraction of natural phenomena, and his studies of metaphysics dealt with the negation or nonexistence of a complex reality. His most famous work in logic was the Tattvacintāmaṇidīdhiti, a commentary on the Tattvacintāmaṇi of Gangeśa Upādhyāya, founder of the Navya Nyāya school.