Transmissions began on 7 February 1966. Programming initially occupied just one hour daily, broadcast on the local frequencies of Rete 2 (today's Rai 2) between 20.00 and 21.00. On 15 December 1979 Rai Sender Bozen began broadcasting on its own dedicated channel.
Unlike all other RAI channels, Rai Südtirol is not on air 24/7. It also broadcasts for different periods of time day by day. Outside its own broadcasting hours, Sender Bozen's frequencies are used by Rai 3.