Reading and Leeds 2013 presale tickets went on sale on 30 August 2012. Weekend tickets were made available on 30 November 2012 at a price of £202.50 (plus an £8 booking fee). Day tickets cost £90.00 (plus a £7 booking fee).
Early entry tickets for the Reading site sold out on 17 June 2013. On 5 July 2013, Saturday day tickets for the Reading site sold out. On 12 July 2013, Friday day tickets for the Reading site sold out. On 23 July 2013, weekend tickets for the Reading site sold out. On 13 August 2013, Sunday tickets sold out, meaning at the Reading site, the full weekend was sold out. On 17 August 2013, Friday tickets for the Leeds site sold out.
On 27 June 2013, Brand New who were due to play on the Main Stage announced that they were cancelling their August European dates including their performances at the Reading and Leeds Festivals. They were replaced by EarlWolf.
Iggy Azalea cancelled in order to attend the MTV Video Music Awards. 
Due to illness, DIIV were forced to cancel Reading and Leeds performances. 
Weekend tickets cost £192.50 before booking fees. Pulp headlined over The Strokes at the Leeds Festival. Mouthwash pulled out due to the split up of the band, they were replaced by Fighting Fiction. The Twilight Singers pulled out and were replaced by Young Legionnaire. OFWGKTA pulled out of the Leeds Festival due to the 2011 MTV Video Music Awards, but still performed at the Reading Festival. Jane's Addiction were due to headline the NME/Radio 1 Stage but cancelled both their appearances at the last minute - after arriving at the Reading site - due to frontman Perry Farrell falling ill. Rise Against played a secret acoustic set on the BBC Introducing Stage at Reading after their mainstage slot.
The festival ran from Friday 22 - Sunday 24 August 2008. Weekend tickets cost £155. Day tickets cost £65.
Set Your Goals pulled out of the festival. Alkaline Trio pulled mainland festival appearances but still appeared at Reading/Leeds.
The Pigeon Detectives appeared on the Dance To The Radio Stage (an alias for the BBC Introducing Stage in reference to their label) on Thursday 21st at the Leeds Site. .
Slipknot pulled out of the festival after drummer Joey Jordison broke his ankle. Feeder were their replacement as far as the slot was concerned, as almost every act below them were moved up a slot, with Bring Me the Horizon being booked instead, although not taking their slot and being at the bottom of the schedule. .
Avenged Sevenfold performed a shortened set at Leeds and pulled out of the Reading leg due to illness. Due to the short notice, they were not replaced and the schedule was re-arranged. This meant Mindless Self Indulgence playing before Feeder, although this not an official 4th and are still retroactively listed as the second band to play.
Kaiser Chiefs played a secret slot on the Carling Stage at the Leeds leg of the event under the pseudonym of 'Hooks for Hands'. Peeping Tom were due to perform on the dance stage, but pulled out. +44 also dropped out.
A weekend ticket cost £145 (plus a maximum of £7 booking fee).
Shortly after the first line-up announcement, Feeder and Yeah Yeah Yeahs switched days, meaning that Yeah Yeah Yeahs would play Reading on Friday and Leeds on Saturday, and that Feeder would play Reading on Saturday and Leeds on Sunday. Audioslave pulled out of their slot due to the band being busy recording new material, The Shins pulled out for undisclosed reasons, and From First to Last pulled out due to the then lead singer (Sonny Moore) needing throat surgery, Paramore had to pull out because their singer (Hayley Williams) had throat problems and were replaced by Sonic Boom Six lower in the bill. Story of the Year and Bleeding Through also pulled out for undisclosed reasons. Flogging Molly played twice at both festivals, once in the punk tent and once on the main stage. Tickets were £135 for a weekend ticket and £60 for a day ticket.
2005 saw My Chemical Romance play both Reading and Leeds on the same day, in an alteration from the original schedule, due to the MTV Video Music Awards. The Transplants were originally booked to play the festivals but pulled out in mid-August due to illness. Jimmy Eat World also pulled out due to other commitments. Other drop outs include Willy Mason, Simple Plan and Fall Out Boy (also due to the VMAs). A weekend ticket cost £125, a day ticket £60.
On the Radio 1 Stage, the Super Furry Animals headlined on the Leeds Saturday, with Graham Coxon second. This order was reversed when the bands played the Reading Friday. New Found Glory pulled out a few weeks before the festival. A weekend ticket cost £105, a day ticket £45.
Black Rebel Motorcycle Club played as a replacement for The White Stripes, who pulled out after Jack White was in a car crash with his then-girlfriend, Renée Zellweger. Although they played second on the Main Stage, it was billed as with Black Rebel Motorcycle Club, reflecting their smaller status. Jay-Z also pulled out, with The Darkness moving further up the bill to replace him. The Libertines were without Pete Doherty, who was at that time estranged from the band; he also missed their 2004 appearance. Other drop outs included Courtney Love, Lostprophets and Godsmack. A weekend ticket cost £95, a day ticket £40.
Guns N' Roses played only in Leeds as they had a prior touring commitment in London on the day of the Reading event. In Reading they were replaced by Raging Speedhorn who appeared much lower on the bill. A weekend ticket cost £90, a day ticket was £39. Reel Big Fish pulled out of Leeds for undisclosed reasons. Antipop Consortium cancelled their Dance Stage appearance after they disbanded earlier that month. Feeder were invited by Melvin Benn to headline the main stage on the first day at Reading and the second day at Leeds. They later turned this down, as they did not want to play such a high profile slot so soon after the death of their drummer Jon Lee in January of that year. As a result, Feeder would instead headline the Radio 1 Evening Session Stage.