Receptor tyrosine kinase-like orphan receptor

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receptor tyrosine kinase-like orphan receptor 1
Identifiers
Symbol ROR1
Alt. symbols NTRKR1
Entrez 4919
HUGO 10256
OMIM 602336
RefSeq NM_005012
UniProt Q01973
Other data
Locus Chr. 1 p32-p31
receptor tyrosine kinase-like orphan receptor 2
Identifiers
Symbol ROR2
Alt. symbols NTRKR2, BDB, BDB1
Entrez 4920
HUGO 10257
OMIM 602337
RefSeq NM_004560
UniProt Q01974
Other data
Locus Chr. 9 q22

In the field of molecular biology, receptor tyrosine kinase-like orphan receptors (RORs) are a family of tyrosine kinase receptors that are important in regulating skeletal and neuronal development, cell migration and cell polarity. ROR proteins can modulate Wnt signaling by sequestering Wnt ligands.[1]

References[edit]

  1. ^ Green JL, Kuntz SG, Sternberg PW (November 2008). "Ror receptor tyrosine kinases: orphans no more". Trends Cell Biol. 18 (11): 536–44. doi:10.1016/j.tcb.2008.08.006. PMID 18848778.