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The Regenstrief Institute, Inc. is a private, non-profit research organization affiliated with the Indiana University School of Medicine (IUSM) and based in Indianapolis. It was founded in 1969 by Sam Regenstrief. The institute is involved in the field of medical informatics and health services research.
Many of Regenstrief's efforts in health services research and development collaborate with the medical informaticians and affiliated organizations at the Indiana University School of Medicine. 
Medical record system
Since the 1970s, this group has been developing the Regenstrief Medical Records System, one of the earliest electronic medical record systems (EMR). This system serves as the production electronic medical records system at Wishard Hospital and its community clinics and other institutions.
Open source medical records system
Regenstrief, in collaboration with Partners In Health (Boston) and MRC (South Africa), helped to found the OpenMRS, an open source effort to build a framework for electronic medical records development in resource poor areas. OpenMRS was selected as Google Summer of Code 2007 project.
- Medical informatics
- Clinical medicine
- electronic medical record systems (EMR)
- Regional Health Information Organization (RHIO)
- Health information exchange (HIE)
- Arden syntax
- National Resource Center for Health Information Technology