Relcovaptan

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Relcovaptan
Relcovaptan.png
Systematic (IUPAC) name
1-({(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-3-hydroxy-2,3-dihydro-1H-indol-2-yl}carbonyl)-L-prolinamide
Clinical data
Legal status
?
Identifiers
CAS number 150375-75-0 YesY
ATC code None
PubChem CID 60943
ChemSpider 54910 N
UNII C1GL8G6G0O YesY
ChEMBL CHEMBL419667 N
Synonyms (2S)-1-[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-(3,4-dimethoxyphenyl)sulfonyl-3-hydroxy-2H-indole-2-carbonyl]pyrrolidine-2-carboxamide
Chemical data
Formula C28H27Cl2N3O7S 
Mol. mass 620.501
 N (what is this?)  (verify)

Relcovaptan (SR-49059) is a non-peptide vasopressin receptor antagonist, selective for the V1a subtype.[1] It has shown positive initial results in tests against Raynaud's disease, dysmenorrhoea, and tocolysis,[2] although it is not yet approved for clinical use.

References[edit]

  1. ^ Lemmens-Gruber R, Kamyar M. Vasopressin antagonists. Cellular and Molecular Life Sciences. 2006 Aug;63(15):1766-79. PMID 16794787
  2. ^ Decaux G, Soupart A, Vassart G. Non-peptide arginine-vasopressin antagonists: the vaptans. Lancet. 2008 May 10;371(9624):1624-32. PMID 18468546