Reversine

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Reversine
Reversine.png
Identifiers
CAS number 656820-32-5 YesY
PubChem 210332
ChemSpider 182286 N
MeSH C484369
ChEBI CHEBI:CHEBI:70723 N
Jmol-3D images Image 1
Properties
Molecular formula C21H27N7O
Molar mass 393.48538
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Reversine, or 2-(4-morpholinoanilino)-6-cyclohexylaminopurine, is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation.

It also has the potential to induce selectively cell death of cancer cells.

References[edit]

  • Chen S, Zhang Q, Wu X, Schultz PG, Ding S (2004) Dedifferentiation of lineage-committed cells by a small molecule. J. Am. Chem. Soc., 126(2):410–411. [PMID 14719906]
  • Chen S, Takanashi S, Zhang Q, Xiong W, Zhu S, Peters EC, Ding S, Schultz PG (2007) Reversine increases the plasticity of lineage-committed mammalian cells. Proc Natl Acad Sci U S A. 104(25):10482-7. [PMID 17566101]

External links[edit]