Revospirone

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Revospirone
Revospirone.png
Systematic (IUPAC) name
1,1-dioxo-2-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]-1,2-benzothiazol-3-one
Clinical data
Legal status ?
Identifiers
CAS number 95847-87-3
ATC code None
PubChem CID 72024
ChemSpider 65018
UNII 6X8764TW2J YesY
Chemical data
Formula C18H21N5O3S 
Mol. mass 387.46 g/mol

Revospirone (Bay Vq 7813) is an azapirone drug which was patented as a veterinary tranquilizer but was never marketed.[1] It acts as a selective 5-HT1A receptor partial agonist.[2] Similarly to other azapirones such as buspirone, revospirone produces 1-(2-pyrimidinyl)piperazine (1-PP) as an active metabolite.[2] As a result, it also acts as an α2-adrenergic receptor antagonist to an extent.[2]

References[edit]

  1. ^ F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1744. ISBN 978-0-412-46630-4. Retrieved 13 May 2012. 
  2. ^ a b c Löscher W, Witte U, Fredow G, Traber J, Glaser T (September 1990). "The behavioural responses to 8-OH-DPAT, ipsapirone and the novel 5-HT1A receptor agonist Bay Vq 7813 in the pig". Naunyn-Schmiedeberg's Archives of Pharmacology 342 (3): 271–7. PMID 2149168.