|Molar mass||133.19 g·mol−1|
|Melting point||165 to 169 °C (329 to 336 °F; 438 to 442 K)|
|S-phrases||S22 S26 S39|
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
|what is: / ?)(|
Some rhodanine derivatives have pharmacological properties; for instance, epalrestat is used to treat diabetic neuropathy. However, most are promiscuous binders with poor selectivity; as a result, this class of compounds is viewed with suspicion by medicinal chemists.
- Rhodanine at Sigma-Aldrich
- C. Ernst Redemann; Roland N. Icke; Gordon A. Alles (1955). "Rhodanine". Org. Synth.; Coll. Vol. 3, p. 763
- J.B. Baell, G.A. Holloway (2010). "New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays". J. Med. Chem. 53 (7): 2719–2740. doi:10.1021/jm901137j. PMID 20131845.
- Tomašić, Tihomir; Peterlin Mašič, Lucija (2012). "Rhodanine as a scaffold in drug discovery: A critical review of its biological activities and mechanisms of target modulation". Expert Opinion on Drug Discovery: 1. doi:10.1517/17460441.2012.688743.
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