|Jmol-3D images||Image 1|
|Molar mass||133.19 g mol−1|
|Melting point||165-169 °C|
|S-phrases||S22 S26 S39|
| (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Some derivatives of rhodanine have pharmacological properties, such as epalrestat which is used to treat diabetic neuropathy. However, most are promiscuous binders with poor selectivity and as a result this class of compounds is viewed with suspicion by medicinal chemists.
- Rhodanine at Sigma-Aldrich
- C. Ernst Redemann; Roland N. Icke; Gordon A. Alles (1955), "Rhodanine", Org. Synth.; Coll. Vol. 3: 763
- J.B. Baell, G.A. Holloway (2010). "New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays". J. Med. Chem. 53 (7): 2719–2740. doi:10.1021/jm901137j. PMID 20131845.
- Tomašić, Tihomir; Peterlin Mašič, Lucija (2012). "Rhodanine as a scaffold in drug discovery: A critical review of its biological activities and mechanisms of target modulation". Expert Opinion on Drug Discovery: 1. doi:10.1517/17460441.2012.688743.
|This article about a heterocyclic compound is a stub. You can help Wikipedia by expanding it.|