An native of Arlington, Virginia, Lowry attended the University of Virginia where he majored in English and history. After graduating, he worked for Charles Krauthammer as a research assistant. He joined William F. Buckley's National Review in 1992, after tying for second place in the magazine's Young Writer's Contest. He was named editor of the magazine in 1997. 
In 2009, Lowry and Keith Korman wrote Banquo's Ghosts, a political thriller. The plot revolves around a nuclear-armed Iran and an inebriated leftist journalist. 
Opinions and ideas
He has been a stalwart opponent of President Barack Obama on all fronts. He has run notorious covers dubbing Michelle Obama "Mrs. Grievance" and portraying President Obama as a doctor donning a latex glove. He called for the repeal of Obamacare immediately upon its passage.
He was a defender of President George W. Bush, although he dissented from his conduct of the Iraq war and was an early advocate of the surge. He broadly supported Bush's foreign policy while criticizing the excesses of the "freedom doctrine." In these years, he became disenchanted with the course of congressional Republicans, whom he characterized as rudderless and corrupt.
He supported the impeachment of President Bill Clinton, but has praised him for his relative centrism compared to Barack Obama.
Following the 2008 Vice Presidential debate between Joe Biden and Sarah Palin, Lowry gained some publicity  and was selected as then-MSNBC commentator Keith Olbermann's Worst Person in the World for writing: "A very wise TV executive once told me that the key to TV is projecting through the screen. It's one of the keys to the success of, say, a Bill O'Reilly, who comes through the screen and grabs you by the throat. Palin too projects through the screen like crazy. I'm sure I'm not the only male in America who, when Palin dropped her first wink, sat up a little straighter on the couch and said, 'Hey, I think she just winked at me.' And her smile. By the end, when she clearly knew she was doing well, it was so sparkling it was almost mesmerizing. It sent little starbursts through the screen and ricocheting around the living rooms of America. This is a quality that can't be learned; it's either something you have or you don't, and man, she's got it."
In 2002, Muslim organizations called for Lowry to apologize, after he posted a message on National Review Online's blog, "The Corner", discussing the "nuking" of Mecca, as retaliation for a terrorist attack.
Lowry grew up in Arlington, Virginia where he attended Yorktown High. He is a Yankees fan. He lives in New York City.
- Lincoln Unbound
- National Review Changing Editor. The New York Times. 5 Nov. 1997.
- Lowry, Richard (2003). Legacy: Paying the Price for the Clinton Years. New York: Regnery Publishing. ISBN 0-89526-129-4.
- Lowry. Legacy. p. 2.
- Blum, William. The Anti-Empire Report. Foreign Policy Journal. 8 June 2009.
- The Campaign Against Mukasey, RealClearPolitics
- Mukasey Questioned on Torture, Clinton Attacked by Opposition. PBS NewsHour. November 2, 2007]
- Lowry, Rich. Circumstances Matter. National Review. 2 Nov 2007.
- Because I Said So
- NR's Rich Lowry: Palin "Sent Little Starbursts Through The Screen"
- Palin's Little Starbursts
- Rich Lowry In Love
- Olbermann, Keith (October 3, 2008). "'Countdown with Keith Olbermann' for Friday September 3, 2008 (sic) (actually October 3)". MSNBC. Retrieved May 3, 2009.
- Olbermann, Keith (October 3, 2008). Lowry's debate review or soft core porn? (streaming) (News commentary program). New York, NY: MSNBC. Retrieved May 3, 2009.
- National Review Editor Suggests "Nuking Mecca" CounterPunch
- The Corner, National Review Online
- That's Rich The American Prospect
- Lincoln Unbound
- National Review Columns
- Columns at TownHall.com
- Video discussion/debate with Lowry and Michael Tomasky on Bloggingheads.tv
- Rich Lowry on Charlie Rose