|Richard H. Scheller|
October 30, 1953|
|Institutions||Genentech, University of California San Francisco|
|Alma mater||University of Wisconsin–Madison, California Institute of Technology, Columbia University|
|Doctoral advisor||Eric H. Davidson|
|Other academic advisors||Eric Kandel, Richard Axel|
|Known for||Head of gRED|
|Notable awards||NAS Award in Molecular Biology (1997)
Kavli Prize (2010)
Albert Lasker Award for Basic Medical Research (2013)
Richard H. Scheller (born 30 October 1953) is the Executive Vice President of Research and Early Development at Genentech. He was a Professor at Stanford University from 1982 to 2001 before joining Genentech. He has been awarded the Alan T. Waterman Award in 1989, the W. Alden Spencer Award in 1993 and the NAS Award in Molecular Biology in 1997, won the 2010 Kavli Prize in Neuroscience with Thomas C. Südhof and James E. Rothman, and won the 2013 Albert Lasker Award for Basic Medical Research with Thomas Sudhof. He was also given the Life Sciences Distinguished Alumni Award from University of Wisconsin–Madison. He is a Fellow of the American Academy of Arts and Sciences and a Member of the National Academy of Sciences.
He earned his B.S. in biochemistry from the University of Wisconsin–Madison and his Ph.D. in chemistry from the California Institute of Technology under the guidance of Eric H. Davidson. While a graduate student, he worked with Keiichi Itakura and Arthur Riggs to help synthesize Somatostatin for Herb Boyer at Genentech. After finishing his graduate studies, he did a brief postdoc with Davidson and later with Eric Kandel and Richard Axel at Columbia University. While at Columbia, he extended his previous work with recombinant DNA to identify the egg-laying hormone (ELH) gene family of neuropeptides.
Richard joined the Stanford University faculty in the Department of Biological Sciences in 1982 and later the Department of Molecular and Cellular Physiology. He was an investigator with the Howard Hughes Medical Institute from 1990 to 2001. While at Stanford, he cloned and identified the proteins that control neurotransmitter release notably those in the Syntaxin family of transport proteins, Rab GTPases, and SNAREs.
In 2001, he was recruited from Stanford to join Genentech as a Senior Vice President and Chief Research Officer replacing Dennis Henner. In 2008, was named the Chief Scientific Officer and Executive Vice President of Research. After the acquisition of Genentech by Hoffmann-La Roche, he was appointed the Head of Genentech Research and Early Development and a member of the enlarged Roche Corporate Executive Committee. He is concurrently an Adjunct Professor in the Department of Biochemistry and Biophysics at the University of California San Francisco.
- Alan T. Waterman Award 1989
- W. Alden Spencer Award 1993
- NAS Award in Molecular Biology 1997
- Life Sciences Distinguished Alumni Award from University of Wisconsin-Madison
- Kavli Prize in Neuroscience 2010
- Albert Lasker Award for Basic Medical Research 2013
He is married to Susan McConnell, a Professor in the Department of Biology at Stanford University and lives on Stanford Campus.
- "Richard Scheller (KavliPrize.no)". Retrieved 24 August 2012.
- "Studies of cloned repetitive DNA sequences in the sea urchin genome"
- "Richard Scheller/Autobiography". Retrieved 24 August 2012.
- "Richard Axel - Autobiography". Nobelprize.org. Retrieved 24 August 2012.
- "Richard H. Scheller, Ph.D.". Howard Hughes Medical Institute. Retrieved 24 August 2012.
- Bennett, M.; Calakos, N; Scheller, R. (10 July 1992). "Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones". Science 257 (5067): 255–259. doi:10.1126/science.1321498. PMID 1321498.
- Abate, Tom (22 January 2001). "Genentech Raids Stanford Lab". SF Chronicle. Retrieved 24 August 2012.
- "Roche and Genentech announce organizational and leadership decisions". 14 April 2009. Retrieved 24 August 2012.