The source of the Keekle is to be found at Keekle Head Farm on High Park between Gilgarran and Asby. From there, the river moves gradually southwards via former open cast mine between Frizington and Whitehaven to Cleator, where it becomes subsumed by the River Ehen. The river is noted for its occasional abundance of salmon. Radioactive Landfill is proposed at Keekle Head. There is strong opposition to the proposal to put radioactive waste in the site of the former open cast mine from Radiation Free Lakeland  and others.