Robert Huber

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For the U.S. Representative from Michigan, see Robert J. Huber. For the Wisconsin State Assemblyman, see Robert T. Huber. For the Finnish sport shooter, see Robert Huber (sport shooter).
Robert Huber
Robert-huber.jpg
Robert Huber at the 2010 Lindau Nobel Laureate Meeting
Born (1937-02-20) February 20, 1937 (age 77)
Munich
Nationality Germany
Fields Biochemist
Notable students Peter Colman (postdoc)[1][2][3]
Known for Cyanobacteria Crystallography
Notable awards
Website
www.biochem.mpg.de/en/eg/huber

Robert Huber ForMemRS is a German biochemist and Nobel laureate.[5][6][7][8][9]

Education and early life[edit]

He was born 20 February 1937 in Munich where his father, Sebastian, was a bank cashier. He was educated at the Humanistisches Karls-Gymnasium from 1947 to 1956 and then studied chemistry at the Technische Hochschule, receiving his diploma in 1960. He stayed, and did research into using crystallography to elucidate the structure of organic compounds.

Career[edit]

In 1971 he became a director at the Max Planck Institute for Biochemistry where his team developed methods for the crystallography of proteins.

In 1988 he received the Nobel Prize for Chemistry jointly with Johann Deisenhofer and Hartmut Michel. The trio were recognized for their work in first crystallizing an intramembrane protein important in photosynthesis in purple bacteria, and subsequently applying X-ray crystallography to elucidate the protein's structure.[10] The information provided the first insight into the structural bodies that performed the integral function of photosynthesis. This insight could be translated to understand the more complex analogue of photosynthesis in cyanobacteria[11] which is essentially the same as that in chloroplasts of higher plants.


He has recently taken up a post at the Cardiff University and will spearhead the development of Structural Biology at the university on a part-time basis.[citation needed]

Since 2005 he has been doing research at the Center for medical biotechnology of the University of Duisburg-Essen.

Huber was one of the original editors of the Encyclopedia of Analytical Chemistry

Awards and honours[edit]

In addition to winning the Nobel Prize for Chemistry, Huber was elected a Foreign Member of the Royal Society (ForMemRS) in 1993. His nomination reads:

Personal life[edit]

Huber is married with four children.[citation needed]

References[edit]

  1. ^ Huber, R; Deisenhofer, J; Colman, P. M.; Matsushima, M; Palm, W (1976). "Crystallographic structure studies of an IgG molecule and an Fc fragment". Nature 264 (5585): 415–20. doi:10.1038/264415a0. PMID 1004567. 
  2. ^ Huber, R; Deisenhofer, J; Colman, P. M.; Epp, O; Fehlhammer, H; Palm, W (1976). "Proceedings: X-ray diffraction analysis of immunoglobulin structure". Hoppe-Seyler's Zeitschrift fur physiologische Chemie 357 (5): 614–5. PMID 964922. 
  3. ^ Colman, P. M.; Deisenhofer, J; Huber, R (1976). "Structure of the human antibody molecule Kol (immunoglobulin G1): An electron density map at 5 a resolution". Journal of molecular biology 100 (3): 257–78. PMID 1255713. 
  4. ^ a b "EC/1999/43: Huber, Robert". London: The Royal Society. Archived from the original on 2014-10-12. 
  5. ^ Engh, R. A.; Huber, R. (1991). "Accurate bond and angle parameters for X-ray protein structure refinement". Acta Crystallographica Section a Foundations of Crystallography 47 (4): 392. doi:10.1107/S0108767391001071. 
  6. ^ Groll, M; Ditzel, L; Löwe, J; Stock, D; Bochtler, M; Bartunik, H. D.; Huber, R (1997). "Structure of 20S proteasome from yeast at 2.4 a resolution". Nature 386 (6624): 463–71. doi:10.1038/386463a0. PMID 9087403. 
  7. ^ Deisenhofer, J.; Epp, O.; Miki, K.; Huber, R.; Michel, H. (1984). "X-ray structure analysis of a membrane protein complex". Journal of Molecular Biology 180 (2): 385. doi:10.1016/S0022-2836(84)80011-X. 
  8. ^ Robert Huber autobiographical information at www.nobel.org
  9. ^ Huber, R.; Swanson, R. V.; Deckert, G.; Warren, P. V.; Gaasterland, T.; Young, W. G.; Lenox, A. L.; Graham, D. E.; Overbeek, R.; Snead, M. A.; Keller, M.; Aujay, M.; Feldman, R. A.; Short, J. M.; Olsen, G. J. (1998). Nature 392 (6674): 353. doi:10.1038/32831. 
  10. ^ Deisenhofer, J.; Epp, O.; Miki, K.; Huber, R.; Michel, H. (1985). "Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution". Nature 318 (6047): 618. doi:10.1038/318618a0. 
  11. ^ Guskov, A.; Kern, J.; Gabdulkhakov, A.; Broser, M.; Zouni, A.; Saenger, W. (2009). "Cyanobacterial photosystem II at 2.9-Å resolution and the role of quinones, lipids, channels and chloride". Nature Structural & Molecular Biology 16 (3): 334. doi:10.1038/nsmb.1559.