Very little is known of Sempill's life. He appears to have spent some time in Paris. He was probably a soldier, and must have held some office at the Scottish court, as his name appears in the Lord Treasurer's books in February 1567 – 1568, and his writings show him to have had an intimate knowledge of court affairs. He was a bitter opponent of Queen Mary and of the Catholic Church. Sempill was present at the siege of Leith (1559-1560), was in Paris in 1572, but fled the country after the massacre of St Bartholomew. He was probably present at the siege of Edinburgh Castle serving with the army of James Douglas, Earl of Morton.
His chief works are:
- The Ballat maid vpoun Margret Fleming callit the Flemyng bark
- The defence of Crissell Sande-landis
- The Claith Merchant or Ballat of Jonet Reid, ane Violet and Ane Quhyt, all three in the Bannatyne manuscript
They are characterized by extreme coarseness, and are probably among his earlier works. His chief political poems are:
- The Regentis Tragedie, a broadside of 1570
- The Sege of the Castel of Edinburgh (1573), interesting from an historical point of view
- Ane Complaint vpon fortoun ... (1581)
- The Legend of the Bischop of St Androis Lyfe callit Mr Patrik Adamsone (1583)
Some of his poems and ballads were intended to advance the cause of the King's side during the Marian civil war. Anonymous printed ballads such as The tressoun of Dumbertane, Robert Lekprevik, Edinburgh (1570), have been attributed to Sempill. The Tressoun describes Lord Fleming's failed ambush of the English commander William Drury at Dumbarton Castle.
Modern editions of Sempill are: Sege of the Castel of Edinburgh, a facsimile reprint with introduction by David Constable (1813); The Sempill Ballates (TG Stevenson, Edinburgh, 1872) containing all the poems; Satirical poems of the Reformation (ed. James Cranstoun, Scottish Text Soc., 2 vols, 1889-1893) with a memoir of Sempill and a bibliography of his poems.
- This article incorporates text from a publication now in the public domain: Chisholm, Hugh, ed. (1911). Encyclopædia Britannica (11th ed.). Cambridge University Press.
- Calendar of State Papers Scotland, vol. 3, (1903), 177: The tressoun of Dumbarton, 15 May, Robert Lekprevik, Edinburgh, 1570: Cranstoun, James, ed., Satirical Poems of the Reformation, vol. 1 (1892) 170-173, & notes vol. 2 (1893), 113-7