Prestia worked with the band for the next three decades, then he became seriously ill in 2001. His fans and friends created a foundation in order to help pay the artist's medical costs. On December 5, 2014, Tower of Power's official website announced that Rocco underwent surgery, and updates would be posted as they became available.
Francis Rocco Prestia has built one of the pillars which support the modern electric bass. He is a master of fingerstyle funk, a technique that he interprets in a very personal way. Prestia lightly mutes the strings with his left hand to get a percussive sound with the pitch remaining clear and accurate. That characteristic sound, in combination with a highly inventive melodic approach to bass lines makes Prestia's sound unmistakable.
Prestia's primary instruments are his Fender Precision basses (a purple transparent American Deluxe and a natural ash-bodied short-lived signature model with a reverse split pickup and a 2-band EQ). In recent years he has maintained an association with the Conklin company that provided him a custom built four-string instrument, one of the few in the company's catalog.
In January 2013, ESP Guitars announced that Prestia has joined their roster of endorsed artists. The company made reference to the introduction of their LTD RB series in May 22, 2014.