The Roman Catholic Church in French Guiana is part of the worldwide Roman Catholic Church, under the spiritual leadership of the Pope in Rome.
Around 75% of the population is Catholic and the dependency forms a single diocese - the Diocese of Cayenne.
Erected as the apostolic prefecture of French Guiana-Cayenne in 1651, it remained a prefecture until elevated to a Vicariate in January 1933, and finally to the Diocese of Cayenne in February 1956. The Diocese is currently a suffragan of the Archdiocese of Fort-de-France et Saint-Pierre on the island of Martinique. The current bishop is Emmanuel Marie Philippe Louis Lafont, appointed in June 2004.