Because he had a Juris Doctor in Law degree, Mix was nicknamed "The Intellectual Assassin" for his physical play. Mix was called for a mere two holding penalties in ten years.
Mix, who was listed at 6' 5" and 270 pounds, was an early proponent of weightlifting to enhance athletic power. He was years ahead of the curve that soon at lineman and other football players taking up that practice to become better athletes. His lifts included a military press of 300 pounds, a clean and jerk of 325 pounds, and a bench press of 425 pounds, all of the lifts considered to be exceptionally strong for that era of play.
Although the Baltimore Colts picked him number 1 in 1960, he chose to go to the AFL, where he had also been the number 1 draft pick.
He was elected to the AFL All-Star team for nine straight years as a Charger, is a member of the All-time All-AFL Team, and is one of only 20 men who played the entire 10 years of the AFL. He was the first Charger to have his number retired in 1969 after he announced he was quitting football after playing injured that season. He earned a law degree from the University of San Diego in 1970. He told the Chargers he wanted play again, but they had found a replacement in Gene Ferguson. After Mix asked to be traded to the New York Jets, San Diego traded him to the Oakland Raiders for two high draft picks in 1970 and 1971. The deal was contingent upon Mix unretiring and agreeing to play for Oakland. He played with the Raiders in 1971. Then-Chargers owner Gene Klein, who hated the Raiders, unretired Mix's number.
He was voted to the Pro Football Hall of Fame in 1979. Mix is Jewish, and was also elected a member of the International Jewish Sports Hall of Fame, being elected to that in 1980. He was the second player from the AFL to be inducted into the Pro Football Hall of Fame. Lance Alworth was the first in 1978.
Mix currently practices law in San Diego, California with a practice focused on representing retired professional athletes in claims for workers' compensation benefits. Prior to that, he was a civil litigator and received an AV rating, which is the highest rating an attorney can receive for skill and integrity.