In addition to his graphic novel and novel work, Simons also paints backgrounds for animation, including Jackie Chan Adventures and Invader Zim. He painted both issues of Jhonen Vasquez's comic I Feel Sick. Simons works with his wife, illustrator Tavisha Wolfgarth. The two currently produce a biweekly webcomic "@Tavicat". In 2007, he was a frequent guest panelist on the video game and geek culture podcast The Weekly Geek.