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|Molar mass||453.02 g/mol|
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Roseophilin is an antibiotic isolated from Streptomyces griscovirides shown to have antitumor activity. The chemical structure can be considered in terms of two components, a macrotricyclic segment and a heterocyclic side-chain. Several laboratory syntheses of roseophilin (e.g., those of Trost, Furstner, Salamone) are based upon the Paal-Knorr synthesis, and two others are based on the Nazarov cyclization reaction (those of Tius, Frontier).
- Furstner, A. (2003). Angew. Chem., Int. Ed. 42 (3582-3603).
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