Roth's spots are retinal hemorrhages with white or pale centers composed of coagulated fibrin. They are typically observed via fundoscopy (using an ophthalmoscope to view inside the eye) or slit lamp exam.
They are usually caused by immune complex mediated vasculitis often resulting from bacterial endocarditis. Roth's spots may be observed in leukemia, diabetes, subacute bacterial endocarditis, pernicious anemia, ischemic events, and rarely in HIV retinopathy.
Roth's spots are named after Moritz Roth.
- ^ synd/2684 at Who Named It?
- ^ M. Roth. Über Netzhautaffectionen bei Wundfiebern. I. Die embolische Panophthalmitis. Deutsche Zeitschrift für Chirurgie, Leipzig, 1872, 1: 471-484.