Route 4 is a national route of Uruguay. In 1975, it was assigned the name Andrés Artigas, a national hero of Uruguay. One fragment of it splits off Route 5 at Carlos Reyles of Durazno Department and ends at Route 20 in Río Negro Department, while a longer part starts off Route 90 in Paysandú Department near Guichón and connects with the city of Artigas in the north. The two parts are of a total length of approximately 330 kilometres (210 mi).
- ^ "LEY N° 14.361". República Oriental del Uruguay, Poder Legislativo. 1975. Retrieved 19 July 2011.