Rudolf Zahradník (born October 20, 1928 in Bratislava, then Czechoslovakia, now Slovakia) is a Czech chemist. He has been particularly interested in the relationships between theoretical and experimental characteristics.
He published more than 350 papers and 10 books especially on quantum chemistry problems. From 1993 to 2001 he was the president of the Czech Academy of Sciences. He is a member of the International Academy of Quantum Molecular Science.
Rudolf Zahradník was a Boy Scout and was awarded the Junák bronze cross (1939–1945).