Louise is a rural municipality in the province of Manitoba in Western Canada. It is located in the southern part of the province, on the border with the state of North Dakota in the United States. The 2006 Census reported a population of 819 persons, a 17.2% decline from the 2001 Census figure of 989 persons. The town of Pilot Mound and the village of Crystal City are located geographically within the municipality, although they are not administratively part of it.
According to Statistics Canada, the rural municipality has an area of 932.67 km² (360.11 sq mi). The administratively separate town of Pilot Mound and village of Crystal City are both enclaved by Louise, near its centre.