In May 2010, Ryan Bang entered the Big Brother house along with 10 other Teenternational housemates. After 56 days, he was able to garner enough votes to reach the final episode wherein he won the competition as the 2nd Teen Big Winner by getting 18.70% of the entire votes.
In August 2010, Ryan Bang became one of the judges in Showtime and stayed from August 16, 2010 up to October 8, 2011. He was eliminated on October 8, 2011, only to be saved by Hurado Dimples Romana, who self-evicted to allow Bang to stay but officially evicted. He is Showtime's longest staying judge at 48 weeks.
Aside from being the longest staying judge at Showtime, he formerly hosts 30w POwhz at Studio 23 and stars in the comedy gag show Banana Split.
On December 5, 2010, he joined Kim Atienza in hosting the show Matanglawin.
In the January 1, 2011 episode of Entertainment Live, he was named as one of the biggest breakthrough artists of 2010.
It was announced on May 24, 2011 that he has released a new album entitled "I Lilly Lilly Like It: Ryan Bang Party Party Hits!".
In January 2013, the Bureau of Internal Revenue filed a tax evasion complaint with the Department of Justice against Ryan Bang for failure to pay his 2010 and 2011 taxes. The Bureau of Internal Revenue stated that it was suing him for a tax liability amounting to Php 1.82 million, including surcharges and interests. In February 2013, Bang stated that he would like to make a personal appearance at the BIR in order to apologize for the incident. He was eager to resolve the case soonest, and made the excuse that he was but a high school student in 2010 and at that time he was unaware of his responsibility to the Philippine government in light of his earning income from the entertainment sector.