As a true freshman in 2011, Shazier started 3 of 13 games, recording 58 tackles and three sacks. As a sophomore in 2012, he started all 12 games, recording 115 tackles and five sacks. As a junior in 2013, he started all 14 games, recording 144 tackles and 6 sacks. Shazier was named an All-American.
Shazier managed 5 tackles and 1 assist in his debut against the Browns. In week 3 against the Panthers, Shazier suffered a sprained MCL, and wouldn't be back until week 8 against the Colts, where he had 2 tackles and 2 assists..