He won the 39th and the 40th Tezuka Award. He made his professional manga debut with WORLDS in 1990. All of his works are published by Shueisha under their Shōnen Jump labels. He has also illustrated four light novels and released two comprehensive art books across his career. Two of the series he has worked on have been made into televised anime.
Fujisaki is best known for the series Hōshin Engi, which was adapted into an anime series and a number of radio dramas, as well as having spawned five video games and cameos in a sixth. Hōshin Engi is currently being considered for a remake by Shomei TV. His most recent completed project is an adaptation of Fuyumi Ono's novel Shiki, which has also gone on to be made into an anime.